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  <xs:element id="cntb_CommercialPaperNotIncludedWithCashAndCashEquivalentsNonUSMember" abstract="true" name="CommercialPaperNotIncludedWithCashAndCashEquivalentsNonUSMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_ShortTermInvestmentsFairValueDisclosure" abstract="false" name="ShortTermInvestmentsFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_SubscriptionReceivable" abstract="false" name="SubscriptionReceivable" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_OtherPrepaidExpenseAndCurrentAssets" abstract="false" name="OtherPrepaidExpenseAndCurrentAssets" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_AccruedClinicalManufacturingAndProfessionalExpenseCurrent" abstract="false" name="AccruedClinicalManufacturingAndProfessionalExpenseCurrent" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_SimcerePharmaceuticalCompanyLimitedMember" abstract="true" name="SimcerePharmaceuticalCompanyLimitedMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_ClinicalTrialReportsMember" abstract="true" name="ClinicalTrialReportsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_CurrentManufacturingProcessMember" abstract="true" name="CurrentManufacturingProcessMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_NewManufacturingProcessMember" abstract="true" name="NewManufacturingProcessMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_RevenueRemainingPerformanceObligationVariableConsiderationAmount" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmount" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_RevenueRemainingPerformanceObligationVariableConsiderationAmountLapsed" abstract="false" name="RevenueRemainingPerformanceObligationVariableConsiderationAmountLapsed" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_RevenueNumberOfPerformanceObligations" abstract="false" name="RevenueNumberOfPerformanceObligations" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="cntb_LeaseExpiringInJanuary2028Member" abstract="true" name="LeaseExpiringInJanuary2028Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_LesseeOperatingLeaseLiabilityToBePaidAfterYearTwo" abstract="false" name="LesseeOperatingLeaseLiabilityToBePaidAfterYearTwo" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_PanaceaVentureMember" abstract="true" name="PanaceaVentureMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="cntb_StatutoryReserve" abstract="false" name="StatutoryReserve" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="cntb_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfConsecutiveDaysToReceiveShares" abstract="false" name="ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfConsecutiveDaysToReceiveShares" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="cntb_TreatmentOfRespiratoryDiseasesSegmentMember" abstract="true" name="TreatmentOfRespiratoryDiseasesSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
</xs:schema>
